Ryze

Release a runic blast, dealing ? magic damage. It splits in two, dealing 33% of the damage to the closest two enemies. Each secondary blast splits an additional time.

Bilgewater: Blasts explode on impact, dealing 18% of the damage as physical damage to adjacent enemies.
Demacia: Execute targets below ? Health.
Freljord: Chill targets for 2 seconds and deal ? bonus true damage.
Ionia: Blasts split an additional time, dealing 50% damage.
Ixtal: Gain a random Region's effect on combat start and every 10 seconds.
Noxus: Blasts now pierce targets, dealing 60% reduced damage per enemy hit.
Piltover: Every third cast is Overcharged, dealing 40% more damage.
Shadow Isles: Increase blast damage by ? .
Shurima: Knock up enemies for 0.5 seconds, with a chance to dredge up Gold or Treasures.
Targon: Heal the lowest Health ally for 10% of the damage dealt.
Void: Ignore 30% of enemies' Armor and Magic Resistance.
Yordle: Shrink targets hit, lowering their damage by 8% percent for 4 seconds.
Zaun: Poison targets, dealing 15 magic damage ? times over 4 seconds.